Edward Tuttle
 
                    Education
M.B.A., finance and business policy, Graduate School of Business, The University of Chicago; M.A., University of California, Irvine; B.A., Sarah Lawrence College
Summary of Experience
Mr. Tuttle specializes in helping both new and established companies grow. He is expert in evaluating market and customer needs, developing new products and services, adapting business structures to meet changing competitive requirements, and employing acquisition and divestiture to improve performance. In the area of new product and service development, he has worked with clients to identify the portfolio of innovations that will create the most value and to enhance the effectiveness with which those innovations are developed and brought to market. Mr. Tuttle has assisted clients in expanding their presence in both new and existing markets, evaluating potential investments, and supporting the acquisition and integration of target companies and product lines. For Fortune 100 clients in health care, transportation, and technology, as well as many smaller clients, his projects have often included development of sophisticated models for evaluating market demand, product success, and business options. He writes and speaks frequently on growth and innovation.
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                                                        Survival among patients receiving eteplirsen for up to 8 years for the treatment of Duchenne muscular dystrophy and contextualization with natural history controlsMuscle & Nerve, 2024 
 2024Iff J, Nicolae Done N, Tuttle E, Zhong Y, Wei F, Darras BT, McDonald CM, Mercuri E, Muntoni F 
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                                                        Real-world evidence of Pressure-Enabled Drug Delivery for trans-arterial chemoembolization and radioembolization among patients with hepatocellular carcinoma and liver metastasesCurrent Medical Research and Opinion, 2024 
 2024Cook K, Gupta D, Liu Y, Miller-Rosales C, Wei F, Tuttle E, Katz SC, Marshak R, Kim AY 
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                                                        Real-world evidence of eteplirsen treatment effects in patients with Duchenne muscular dystrophy in the USAJournal of Comparative Effectiveness Research, 2023 
 2023
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                                                        Delays in pulmonary decline in eteplirsen-treated patients with Duchenne muscular dystrophyMuscle & Nerve, 2022 
 2022Iff J, Gerrits C, Zhong Y, Tuttle E, Birk E, Zheng Y, Paul X, Henricson EK, McDonald CM, CINRG-DNHS Investigators 
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                                                        Disease Progression Stages and Burden in Patients with Duchenne Muscular Dystrophy Using Administrative Claims Supplemented by Electronic Medical RecordsAdvances in Therapy, 2022 
 2022Iff J, Zhong Y, Gupta D, Paul X, Tuttle E, Henricson E, Schrader R, CINRG DNHS Investigators 
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                                                        Effects of metreleptin in patients with lipodystrophy with and without baseline concomitant medication useCurrent Medical Research and Opinion, 2021 
 2021Adamski K, Cook K, Gupta D, Morris E, Tuttle E, Carr E, Cremasco F, Cochran E, Brown RJ 
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                                                        Effects of Metreleptin on Patient Outcomes and Quality of Life in Generalized and Partial LipodystrophyJournal of the Endocrine Society, 2021 
 2021Cook K, Adamski K, Gomes A, Tuttle E, Kalden H, Cochran E, Brown RJ 
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                                                        Development of a classifier to identify patients with probable Lennox-Gastaut syndrome in health insurance claims databases via random forest methodologyCurrent Medical Research and Opinion, 2019 
 2019Vekeman F, Piña-Garza JE, Cheng WY, Tuttle E, Giguère-Duval P, Oganisian A, Damron J, Duh MS, Shen V, Saurer TB, Montouris GD, Isojarvi J 
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                                                        Achievement of Glycated Hemoglobin Goals in the US Remains Unchanged Through 2014Diabetes Therapy. Jun 23 2017 
 2017Carls G, Huynh J, Tuttle E, Yee J, Edelman SV 
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                                                        Assessment of treatment patterns and healthcare costs associated with probable Lennox-Gastaut syndromeEpilepsy & Behavior. Aug 2017;73:46-50 
 2017Piña-Garza JE, Montouris GD, Vekeman F, Cheng WY, Tuttle E, Giguere-Duval P, Duh MS, Shen V, Saurer TB, Isojarvi J 
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                                                        Understanding the Gap Between Efficacy in Randomized Controlled Trials and Effectiveness in Real-World Use of GLP-1 RA and DPP-4 Therapies in Patients With Type 2 DiabetesDiabetes Care. 2017;40(11):1469-1478 
 2017Carls GS, Tuttle E, Tan RD, Huynh J, Yee J, Edelman SV, Polonsky WH 
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                                                        Real-world weight change among patients treated with glucagon-like peptide-1 receptor agonist, dipeptidyl peptidase-4 inhibitor and sulfonylureas for type 2 diabetes and the influence of medication adObesity Science and Practice. September 2017;3(3):342-351 
 2017Carls GS, Tan R, Zhu JY, Tuttle E, Yee J, Edelman SV, Polonsky WH 
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                                                        Antibiotic treatment patterns, costs, and resource utilization among patients with community acquired pneumonia: a US cohort studyHospital Practice. Feb 2017;45(1):1-8 
 2017
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                                                        Advanced Diagnostics: Innovation, Reimbursement, and Coverage ChallengesIN VIVO, October 2014 
 2014
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                                                        Authorized Generic Drugs, Price Competition, And Consumers’ WelfareHealth Affairs - 26, no. 3 (2007): 790-799 
 2007Berndt E, Parece A, Tuttle E, Mortimer R, Bhattacharjya A 
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                                                        Prevalence, referral patterns, testing, and surgery in aortic valve disease: leaving women and elderly patients behind?J Heart Valve Dis 2007 Jul;16(4):362-9 
 2007Bach D, Ivanova J, Birnbaum H, Fournier A, Tuttle E 
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                                                        Economic burden and co-morbidities of atrial fibrillation in a privately insured populationCurr Med Res Opin. 2005 Oct;21(10):1693-9. 
 2005Wu EQ, Birnbaum HG, Mareva M, Tuttle E, Castor AR, Jackman W, Ruskin J. 
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                                                        Your Patent Is About to Expire: What Now?Pharmaceutical Executive 2004 Nov. 
 2004Tuttle E, Parece A, Hector A 
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                                                        Beyond Lifecycle Management - Optimizing Performance Following Patent ExpiryWhite Paper 
 2004Tuttle E, Parece A, Hector A 
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                                                        A Comprehensive Approach to Corporate Venturing2001 Handbook of Business Strategy 
 2001Tuttle E, Getz G 
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                                                        Free Radicals: Why Industry Leaders Fail to Harness Disruptive TechnologiesRed Herring 
 1999Tuttle E, Christensen C 
 
         
                                 
                                