Kalé Kponee-Shovein
 
                    Education
Sc.D., epidemiology and environmental health, and Sc.M., biostatistics, Harvard University; M.P.H., epidemiology, Boston University; B.A., psychology and Spanish, Saint Louis University
Summary of Experience
Dr. Kponee-Shovein is an epidemiologist with analytical experience in causal inference methods, outcomes research, drug safety, health economics, and health care litigation. She has a wide range of experience with various types of health care data, including insurance claims, electronic medical records, chart review, clinical trials, and survey data. She has also provided regulatory and strategic consulting on drug registration and real-world evidence generation for US Food and Drug Administration new drug application (NDA), supplemental new drug application (sNDA), and orphan drug designation (ODD) submissions. Dr. Kponee-Shovein has developed and led research projects in resource-poor settings. She has also presented abstracts at conferences on epidemiology and environmental health sciences, and coauthored articles in peer-reviewed journals such as JAMA Internal Medicine and the American Journal of Epidemiology. Dr. Kponee-Shovein is an adjunct lecturer in the epidemiology department at the Harvard T.H. Chan School of Public Health.
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                                                        Gastrointestinal manifestations in pediatric and adult patients with Rett syndrome: an analysis of US claims and physician survey dataJournal of Comparative Effectiveness Research, 2024 
 2024May DM, Neul J, Piña-Garza JE, Kponee-Shovein K, Satija A, Mahendran M, Downes N, Sheng K, Lema N, Boca A, Lefebvre P, Abler V, Youakim JM, Cheng WY 
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                                                        Development of Predictive Models to Inform a Novel Risk Categorization Framework for Antibiotic Resistance in E. coli-Causing Uncomplicated Urinary Tract InfectionClinical Infectious Diseases, 2024 
 2024Shields RK, Cheng WY, Kponee-Shovein K, Indacochea D, Gao C, Kuwer F, Joshi AV, Mitrani-Gold FS, Schwab P, Ferrinho D, Mahendran M, Pinheiro L, Royer J, Preib MT, Han J, Colgan R 
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                                                        Characterizing the journey of Rett syndrome among females in the United States: a real-world evidence study using the Rett syndrome natural history study databaseJournal of Neurodevelopmental Disorders, 2024 
 2024May D, Kponee-Shovein K, Neul JL, Percy AK, Mahendran M, Downes N, Chen G, Watson T, Pichard DC, Kennedy M, Lefebvre P 
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                                                        Epidemiology and Patient Journey of Rett Syndrome in the United States: A Real-World Evidence StudyBMC Neurology, 2023 
 2023May D, Kponee-Shovein K, Mahendran M, Downes N, Sheng K, Lefebvre P, Cheng WY 
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                                                        Impact of choice of inhalers for asthma care on global carbon footprint and societal costs: a long-term economic evaluationJournal of Medical Economics, 2022 
 2022Kponee-Shovein K, Marvel J, Ishikawa R, Choubey A, Kaur H, Ngom K, Fakih I, Swartz N, Schatzki T, Signorovitch J 
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                                                        Estimating the US pericarditis prevalence using National Health Encounter Surveillance DatabasesCurrent Medical Research and Opinion, 2022 
 2022Luis SA, LeWinter MM, Magestro M, DerSarkissian M, Duh MS, Chang R, Kponee-Shovein K, Muthukumar A, Hu X, Lim-Watson MZ, Klein AL 
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                                                        Carbon footprint and associated costs of asthma exacerbation care among UK adultsJournal of Medical Economics, 2022 
 2022Kponee-Shovein K, Marvel J, Ishikawa R, Choubey A, Kaur H, Thokala P, Ngom K, Fakih I, Schatzki T, Signorovitch J 
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                                                        Profiling Disease and Economic Burden in CRSwNP Using Machine LearningJournal of Asthma and Allergy, 2022 
 2022Bhattacharyya N, Silver J, Bogart M, Kponee-Shovein K, Cheng WY, Cheng M, Cheung HC, Duh MS, Hahn B 
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                                                        Suicidal ideation and attempts in the United States of America among stimulant-treated, non-stimulant-treated, and untreated patients with a diagnosis of attention-deficit/hyperactivity disorderJournal of Affective Disorders, April 2020 
 2020Siffel C, DerSarkissian M, Kponee-Shovein K, Spalding W, Gu Y, Cheng M, Duh M 
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                                                        August 24, 2021
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                                                        February 24, 2024
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                                                    July 10, 2024
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                                                    May 22, 2024
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                                                    September 14, 2022
 
         
                                