Arielle Bensimon
Education
Ph.D., health policy, Harvard University; B.A., economics, government, and English, Cornell University
Summary of Experience
Dr. Bensimon specializes in health economics and outcomes research (HEOR) and provides expertise in decision modeling methods for health technology appraisal. She has led the design and implementation of cost-effectiveness and budget impact models in multiple countries, guided the development of several successful regulatory submissions to the UK’s National Institute for Health and Care Excellence (NICE) and Canada’s Drug and Health Technology Agency (CADTH), and closely supported clients throughout the ICER review process in the US. Her work has also included empirical comparative effectiveness studies using large retrospective databases and medical chart reviews, burden-of-illness studies, development of predictive models to estimate health risks, patient-reported outcome (PRO) studies, and analyses of clinical trial data to address a variety of research objectives. Dr. Bensimon has conducted research in a range of therapeutic areas, including oncology indications, diabetes, hypertension, mental health disorders, rare hereditary diseases, and several infectious diseases and autoimmune disorders. Her work has been presented at clinical and economic research conferences and published in various peer-reviewed journals.
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Cost-Effectiveness Analysis of Pembrolizumab as an Adjuvant Treatment of Renal Cell Carcinoma Post-Nephrectomy in the United States
Clinical Genitourinary Cancer, 2023
2023Lai Y, Bensimon AG, Gao E, Bhattacharya R, Xu R, Chevure J, Imai K, Haas NB
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Cost-Effectiveness Analysis of Pembrolizumab as an Adjuvant Treatment of Resected Stage IIB or IIC Melanoma in the United States
Advances in Therapy, 2023
2023Zhang S, Bensimon AG, Xu R, Jiang R, Greatsinger A, Zhang A, Fukunaga-Kalabis M, Krepler C
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The impact of achieving and maintaining near-complete or complete skin clearance on patient quality of life in moderate-to-severe psoriasis
Journal of the American Academy of Dermatology, 2021
2021Ryan C, Puig L, Zema C, Thompson E, Yang M, Wu EQ, Bensimon A, Huang X, Joshi AD, Elewski B
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Health care resource utilization and cost burden of hemophilia B in the United States
Blood Advances, 2021
2021Buckner TW, Bocharova I, Hagan K, Bensimon AG, Yang H, Wu EQ, Sawyer EK, Li N
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Economic Benefit from Improvements in Health-Related Quality of Life with Upadacitinib: Comparisons with Tofacitinib and Methotrexate in Patients with Rheumatoid Arthritis
Advances in Therapy, 2021
2021Bergman M, Tundia N, Yang M, Orvis E, Clewell J, Bensimon A
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Cost-effectiveness of pembrolizumab with axitinib as first-line treatment for advanced renal cell carcinoma
Current Medical Research and Opinion, 2020
2020Bensimon AG, Zhong Y, Swami U, Briggs A, Young J, Feng Y, Song Y, Signorovitch J, Adejoro O, Chakravarty A, Chen M, Perini RF, Geynisman DM
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An Economic Evaluation of Pembrolizumab Versus Other Adjuvant Treatment Strategies for Resected High-Risk Stage III Melanoma in the USA
Clinical Drug Investigation, 2020
2020Bensimon AG, Zhou ZY, Jenkins M, Song Y, Gao W, Signorovitch J, Krepler C, Scherrer E, Wang J, Aguiar-Ibáñez R
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Cost-effectiveness of pembrolizumab for the adjuvant treatment of resected high-risk stage III melanoma in the United States
Journal of Medical Economics, 2019
2019Bensimon AG, Zhou ZY, Jenkins M, Song Y, Gao W, Signorovitch J, Krepler C, Liu FX, Wang J, Aguiar-Ibáñez R
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Real-world durability of relapse rate reduction in patients with multiple sclerosis receiving fingolimod for up to 3 years: a retrospective US claims database analysis
Journal of the Neurological Sciences, 2019
2019Fox E, Vieira MC, Johnson K, Peeples M, Bensimon AG, Signorovitch J, Herrera V
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Cost-effectiveness of ceritinib in previously untreated anaplastic lymphoma kinase-positive metastatic non-small cell lung cancer in the United States
Journal of Medical Economics. Jun 2018;21(6):577-586
2018Zhou ZY, Mutebi A, Han S, Bensimon AG, Louise Ricculli M, Xie J, Dalal A, Culver K
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Efficacy and safety of adalimumab among patients with moderate to severe psoriasis with co-morbidities
Am J Clin Dermatol. 2011 Feb 1;12(1):51-62
2011Kimball A, Bensimon A, Guerin A, Yu AP, Wu EQ, Okun M, Bao Y, Gupta S, Mulani P
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Compliance, persistence, healthcare resource use, and treatment costs associated with aliskiren plus ARB versus ACE inhibitor plus ARB combination therapy
Am J Cardiovasc Drugs. 2011;11(1):21-32
2011Chang J, Yang W, Kahler KH, Fellers T, Orloff J, Bensimon AG, Yu AP, Fan CP, Wu EQ
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Copayment level, treatment persistence, and health care utilization in hypertension patients treated with single-pill combination therapy
J Med Econ. 2011 Mar 30.
2011Yang W, Kahler KH, Fellers T, Orloff J, Chang J, Bensimon AG, Wu EQ, Fan CP, Yu AP
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Comparison of skeletal complications and treatment patterns associated with early vs. delayed zoledronic acid therapy in multiple myeloma
Clin Lymphoma Myeloma Leuk. 2011 Aug;11(4):326-35. Epub 2011 May 6
2011Wu EQ, Bensimon A, Marynchenko M, Namjoshi M, Guo A, Yu AP, Ericson S, Raje N
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Evaluation of compliance and health care utilization in patients treated with single pill vs. free combination antihypertensives
Curr Med Res Opin. 2010 Sep;26(9):2065-76
2010Yang W, Chang J, Kahler K, Fellers T, Orloff J, Wu E, Bensimon A
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Economic consequence of switching to citalopram after its generic entry for adult patients with major depressive disorder (MDD) treated with escitalopram
Journal of Medical Economics, 2010
2010Yu A, Xie J, Bensimon A, Parikh K, Wu E, Ben-Hamadi R, Blum S, Haim Erder